Investors rarely give you 30 minutes. You usually get 30 seconds. That first moment sets the pace for everything that follows. When your opening slide lands cleanly, investors lean in. When it confuses them, their attention slips, and getting it back becomes tough.
In our work with biotech founders, we often see the same truth appear again and again. The strongest decks respect investor attention from the very first frame.
Why the First Slide Carries So Much Weight
Investors are scanning several decks a week, sometimes several a day. Your opener becomes the first filter they use to decide whether your story is worth the next minute. In our experience, that slide has one job. It must give investors confidence that you can explain your science and your market with clarity.
When the first slide tries to do too much, you lose them. When it tries to impress instead of inform, you lose them. When it forces them to guess what you do, you lose them. Fortunately, the fix is simple.
The Pattern We Keep Seeing in Strong Decks
After rebuilding dozens of decks for biotech teams, we typically see the same pattern in slides that hold attention:
Lead with a clear headline
Your headline should say what you do in plain language. Think of it as your elevator line written for someone who reads fast.
Put the problem in plain language
Investors need to see the pain point before they care about your tech. One or two short lines are enough. If a non-scientist on your team can read it once and repeat it, you are on the right track.
Save the science deep dive for later
Your mechanism matters, but not yet. Investors want the destination before the map. The early slides should create confidence that you are solving something real, not overwhelm them with details they have not asked for.
Decks that follow this rhythm tend to open more doors. They make it easy for investors to see the promise early, which buys you time to go deeper on the next slides.
A Practical Example
Imagine a first slide that says:
“A faster, more accurate way to detect X before symptoms appear.”
Then a single line on the problem. Then your logo.
Simple. Direct. Clear. Investors usually appreciate that clarity because it shows you can prioritize what matters.
Resources You Might Find Helpful
You can dive deeper into how we shape scientific stories in our portfolio pages, such as the Sublime Systems brand project or the Medicilon brand refresh on wizardly.co. These examples show how clarity influences design, copy, and overall narrative.
Final Thought
What is the first slide of your deck saying? If it speaks clearly, investors often give you the time you need. If not, this is the perfect moment to sharpen it.

